金曜日, 10. 5月 2019, Chiba Prefecture, 4th International Conference on Enzymology & Molecular Biology (CSE)

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4th International Conference on Enzymology & Molecular Biology

About ConferenceConferenceSeries Ltd organises 1000+ Global Events every year on Clinical, Medicine, Pharma and Science & Technology every year across USA, Europe, Asia, Middle East, Australia and UK with support from 1000 more scientific societies and Publishes 700+ open access journals  which contains over 100000 eminent personalities, reputed scientists as editorial board and organizing committee and Scope:With the success of “3rd  International Conference on Enzymology & Molecular Biology” in London, UK Conference Series Ltd is proud to host upcoming “4th  International Conference on Enzymology & Molecular Biology” during May 10-11,2019 in Tokyo, Japan. This is an excellent opportunity for the delegates from Universities and Institutes to interact with the world class Scientists. The conference revolves around the theme – “Novel Advancements in Enzymology and Molecular Biology”.The broad subject coverage of the Conference and its size provide an excellent setting for participants to gain valuable insight into progress in research areas beyond their own. In addition a range of special sessions aims to engage participants on broader issues such as teaching in the enzymology and molecular biology research.The Enzymology Conference  has a strong emphasis on support and inspiration for the next generation of scientists, along with early-career researchers, a Young Researchers Forum, and activities to encourage interaction with peers and this conference aims to be an extraordinary cross discipline gathering in the enzymology life sciences for research presentations, discussions, learnings, inspirations and encouragement with participants leaving with new research knowledge and ideas, and perhaps the beginnings of international collaborations and Ltd gladly welcomes all the participants from all over the world to join the upcoming prestigious event “4th International Conference on Enzymology and Lipid Science" to be held during September 11-12, 2018 at Singapore City. The conference includes Keynote presentations, Oral/Poster presentations and Exhibitions.    Enzymology Congress 2019 mainly emphasizes on methods such as Biochemical processes, Bio molecular engineering, Immunoassays for protein detection, Mass spectroscopy & protein profiling, Membrane-lipid therapy and Polyunsaturated fatty acids (PUFA).Track-1:  Enzymology & BiochemistryEnzymes are both macromolecular and micromolecular proteins and are found naturally. They are macromolecular biological catalysts and accelerate chemical reactions. Enzymology  deals with the study of enzymes, their kinetics, structure, and function, as well as their relation to each other. Enzymes play a very important role in the world. They act as a catalyst for a chemical reaction, whether that reaction involves the execution of DNA for the purpose of cell repair or for the digestion of any types of meat as well as poultry. Biochemistry is the branch of science which deals with the chemical processes within and related to living organisms. It is a laboratory based science that combines both biology and chemistry. Biochemistry mainly focuses on processes that happen at a molecular level like inside our cells, studying components like proteins, lipids and organelles. It also looks at how cells communicate with each other. Biochemists should understand how the molecular structure relates to its function, and then allow them to predict that how the molecules will interact. Biochemistry covers a range of scientific disciplines, which includes genetics, microbiology, forensics, plant science and Molecular EnzymologyMolecular enzymology  is that branch of biochemistry which encircles or deals with the functional as well as the structural characteristics of the enzymes within a molecular level. Enzymes are globular proteins which play a very important role as a catalyst for any type of biochemical reactions. Molecular enzymology is based on designing and enzyme synthesis and high unmet medical needs are based on innovative drug targets. These works are based on innovative drug targets. Molecular Enzymology's interest include in all aspects related to enzymes like discovery of enzymes, structure of enzymes, enzyme mechanisms, cellular and metabolic functions of enzymes, discovery of drugs, biochemical aspects of enzymes, bioinformatics, computational analysis, studies for molecular modeling, newer methods in enzyme expression as well as purification, bio catalysis, bio molecular engineering, enzyme kinetics and enzyme Clinical EnzymologyClinical enzymology  deals with the measurement of enzyme activity for the diagnosis and treatment of diseases. Enzymes are macromolecular catalysts which increase the rate or velocity of physiologic reactions. Each and every reaction occurring daily in our body takes place with the help of an enzyme or the other. In general, most of the enzymes are present in cells at much higher concentrations than that in plasma. Measurement of these levels in plasma indicates whether their tissue of origin is damaged causing to the release of intracellular components into the blood. This forms the basis of what is called clinical enzymology. Thus we can say that clinical enzymology refers to measurement of enzyme activity for the diagnosis as well as the treatment of diseases.      Track-4:  Structural EnzymologyEnzymes are the group of proteins which process cellular metabolism. They can affect a reaction either by catalysing or they can be used to reverse the reactions in bio-chemical pathways. Though enzymes have complex enzymatic structures, they undergo many changes which is very important for reactions and so enzyme structure is very much essential. There is always a specific enzyme for specific reaction i.e., reactions are enzyme specific in nature. Enzymes structures are made up of a special type of amino acids i.e., α amino acids which are linked together via an amide (peptide) bond in a linear chain. This is the primary structure and the resulting amino acid chain is called a polypeptide chain or rather a 5: Soil EnzymologyEnzymes are the vital activators in life processes, likewise in the soil they are known to play a substantial role in maintaining soil health and its environment. Soil enzymes are critically important to the functioning of the soil. Soil enzymes are the product of soil microorganisms and are the drivers for biogeochemical cycling in soils. Soil enzymes are also involved in remediation of contaminated soils. As a result, soil enzymes have been considered indicators for soil ecosystem health. The enzymatic activity in the soil is mainly of microbial origin, being derived from intracellular, cell-associated or free enzymes. A unique balance of chemical, physical, and biological (including microbial especially enzyme activities) components contribute to maintaining soil health. Evaluation of soil health therefore requires indicators of all these components. Healthy soils are essential for the integrity of terrestrial ecosystems to remain intact or to recover from disturbances, such as drought, climate change, pest infestation, pollution, and human exploitation including agriculture. Deterioration of soil, and thereby soil health, is of concern for human, animal, and plant health because air, groundwater, and surface water consumed by humans, can be adversely affected by mismanaged and contaminated 6: Enzyme KineticsEnzyme kinetics deals with the study of the chemical reactions that are catalyzed mainly by the enzymes. In enzyme kinetics, the rates of the reaction are measured and the effects of varying the conditions of the reaction are studied. Studying the kinetics of an enzyme in this way can reveal the catalytic mechanism of that particular enzyme as well as its role in metabolism, how its activity is being controlled, and how a drug might inhibit that Enzymology in Drug DiscoveryEnzymes are the macromolecular and micromolecular proteins in the drug design that act as drug targets for the diseases in the process of discovery of drugs as well as its development. There are a number of drug targets which are involved in the designing of the drugs. Drug target is a nucleic acid or a protein whose activity can be modified by a drug itself. The drug can be a chemical compound with a small molecular weight or a biological compound, such as an antibody or a recombinant protein. The drug target should be effective in the disease by relevant in vitro or in vivo models and 8: Enzyme ToxicologyEnzyme Toxicology is unremarkable, except the potential irritating effects usually associated with some proteases at high concentrations, and the allergic effects of enzymes. Like anything one is exposed to, the dose makes the poison; thus, with certain enzymes, a sufficient excess in exposure can lead to irritation. Enzymes are like the majority of food proteins so that oral exposure to the gut is entirely without effect, except perhaps at very high, unrealistic, exposure levels Enzymes have been evaluated for genotoxic effects Nevertheless, enzymes are not mutagenic in the standard screening assays used in genetic toxicology, specifically the Ames test, and are not clastogenic in chromosome aberration tests. Repeated exposure studies on a number of enzymes have been completed. Most often this has been done in relation to enzymes to be used in foodstuffs and so exposure has been carried out via the oral route. Track-9: Enzymology & ProteomicsProteomics is the large-scale study related to proteins, mainly their structures and functions. Proteins are the vital parts of all the living organisms, as they form the main components of the physiological metabolic pathways of the cells. The term proteomics was first coined in the year of 1997 to make an analogy with the term genomics, which again deals with the study of the genome. The word proteome is a combination of protein and genome together. The proteome can be said as the entire set of proteins, which are produced or modified by an organism or a Computational EnzymologyMolecular simulations and modelling means altering the science of enzymology. Computational enzymology is a rapidly developing area, and is studying the theories of catalysis, challenging 'textbook' mechanisms, and also identifying the novel catalytic mechanisms. Also increasingly, modelling is contributing directly towards the experimental studies of the enzyme-catalysed reactions. Potential practical applications in this area include interpretation of the experimental datas, catalyst design and also drug 11: Enzyme NanotechnologyThe nanomaterials possess ideal characteristics to equilibrate principal factors which determine biocatalysts efficiency, including specific surface area, mass transfer resistance and effective enzyme loading. This review presents the current scenario and techniques in enzyme immobilization. Some methods are used which are efficient to combine proteins/enzymes with nanoparticles. Immobilization process is to optimize the operational performance of an enzyme for industrial applications. So far different matrices have been described in the literature to improve the performance of the immobilized enzymes. With the advent of nanotechnology, the nanomaterials because of their unique physico-chemical properties constitute novel and interesting matrices for enzyme immobilization.    Enzyme nanoparticles    DNA nanotechnology    Nanotechnology products    DNA microarray    Nanopolymers    Nanotechnology in targeted drug delivery    Immobilization using nanoparticles    Nanotechnology enabled enzyme activityTrack-12: Industrial Applications of EnzymologyEnzymes are used nowadays in chemical industries and for some  industrial purposes where extremely specific catalysts are required for industrial uses. Enzymes in general are rare in number of reactions they have evolved to catalyse and also by the lack of stability in organic solvents and at very high temperatures. Thus, protein engineering is an active an advanced area of research which includes attempts for creating new enzymes with novel properties. These efforts have begun to be successful, and a few enzymes have now been designed to catalyse reactions that do not occur naturally. Enzymes are usually macromolecular and micromolecular protein molecules that manipulate the other molecules i.e., the enzymes substrates. These target molecules binds up to the active site of an enzyme and are thus converted into products via a series of steps which are combined known as the enzymatic : Enzymology & ThermodynamicsIn the presence of an enzyme, the reaction runs in the same direction as it would run without an enzyme, but just more quickly. The reaction rate is dependent on the activation energy which is needed to form the transition state which then transforms into products. Enzymes increase  the reaction rates by decreasing the transition state energy. First, binding forms an enzyme-substrate complex (ES) with low energy. Secondly the transition state is stabilized by the enzyme such that it requires lesser energy to achieve compared to the uncatalyzed reaction (ES‡). Finally the enzyme-product complex (EP) gets dissociated to release the Enzymology in Food Processing & TechnologyFood enzymology deals with all the aspects of the enzymology which are related to the food systems. The basic aspects of the food enzymology are the methods for measuring the enzyme activities; extraction of the enzymes from microbial, plant and animal systems; methods of purification of enzyme as well as its characterization; and regulation of enzymatic activities by activators, inhibitors, and via covalent 15: Lipid and Lipoprotein MetabolismThe total cost of decreasing low-density lipoprotein generally includes the costs of physician services, case finding and monitoring, dietary and exercise modifications, medications, and also treating the side effects. The cost of treatment-related appointments follow-up or varies by type of provider, location, and practice setting. The annual cost of statin drugs to reduce low-density lipoprotein cholesterol levels can range from $1,082 to $1,543 per year.  Although the cost of decreasing the low-density lipoprotein cholesterol levels can be high, but it is much lower than the direct and indirect costs of cardiovascular disease 16: Genomics Genomics is a domain of science that specialize in the structure, function, evolution, mapping, and redaction of genomes. An ordering is an organism's complete set of DNAs, as well as all of its genes. In distinction to biology, that refers to the study of individual genes and their roles in inheritance, genetics aims at the collective characterization and quantification of genes, that direct the assembly of proteins with the help of enzymes and traveler molecules. In turn, proteins compose body structures comparable to organs and tissues still as management chemical reactions and carry signals between cells. Genetics conjointly involves the sequencing and analysis of genomes through uses of high turnout DNA sequencing and bioinformatics to assemble and analyze the perform and structure of entire genomes.  Advances in genetics have triggered a revolution in discovery-based analysis and systems biology to facilitate understanding of even the foremost advanced biological systems comparable to the 17: Molecular GeneticsThe term biology| genetics.  genetic science is currently redundant as a result of up to date genetics is totally molecular. biology isn't created of 2 sciences, one molecular and one non-molecular. all the same, active biologists still use the term. once they do, they're usually concerning a collection of laboratory techniques geared toward distinctive and/or manipulating polymer segments concerned within the synthesis of necessary biological molecules. Scientists typically speak and write of the applying of those techniques across a broad swath of medicine science. For them, genetic science is associate fact-finding approach that involves the applying of laboratory ways and analysis ways. This approach presupposes basic data regarding the expression and regulation of genes at the molecular levelOur Conference will provide a perfect platform addressing:Laudable talks by the top-notch of the global scientific communitySterling workshop sessionsRemarkable Awards and Global Recognition to meritorious ResearchersGlobal Networking with 50+ CountriesNovel Techniques to Benefit Your ResearchGlobal Business and Networking OpportunitiesExquisite Platform for showcasing your products and International Sponsorship
AGENDA 2018-------------------------------------2019 Upcoming Soon-------------------------------------Day 1 March 05, 201808:30-09:00 RegistrationsArmstrong09:00-09:30 Opening CeremonyKeynote Forum09:30-10:10Title: Kinetic and molecular dissection of coupled ion-substrate membrane transportproteinsPeter J F Henderson, Astbury Centre for Structural Molecular Biology - University of Leeds, UK10:10-10:50Title: Mixing enzyme discovery with engineering for sucrose-derived bioproducts: Thecase of GH13 and GH70 polymerasesMagali Remaud Simeon, INSA - Université de Toulouse, FranceGroup PhotoNetworking & Refreshment Break 10:50-11:10 @ Breakout Area11:10-11:50Title: Proteolytic abzymes as translational tools of the newest generation to be exploitedfor biodesign and bioengineeringSergey Suchkov, I M Sechenov First Moscow State Medical University, Russia11:50-12:30 Title: Developing site-specifically modified ADCs using a chemoenzymatic approachDavid Rabuka, Catalent Biologics, USASessions: Industrial Biotechnology| Pharmaceutical Biotechnology |Biotechnology ApplicationsSession Chair: Sergey Suchkov, Moscow State Medical University, RussiaSession Introduction12:30-13:00Title: Efficiency of the antioxidative system is the first prerequisite for effective doubledhaploids production with the use of isolated microspore culture methodIwona Zur, Polish Academy of Sciences, PolandLunch Break 13:00-14:00 @ RBG14:00-14:30Title: Development of approach to obtain Brachypodium distachyon L. regenerative plants withmorphogenetic stabilityOmirbekova N Zh, Al-Farabi Kazakh National University, Kazakhstan14:30-15:00Title:Toxicological aspects of physiological and biochemical changes with potassiumsilicate and silica nano-particles on albino ratHelmi Mohamed El-bendary, Fayoum University, Egypt15:00-15:30Title: Engineering carbon-conserving synthetic pathways for assimilation and conversion of C5/C6carbon sources into added value chemicalsJean M Francois, Université Fédérale Toulouse Midi-Pyrénées, FranceSessions: Structural Enzymology | Enzymology & BiochemistrySession Chair: Magali Remaud-Simeon, INSA-Tolouse, FranceSession Introduction15:30-16:00Title: Molecular enzymology of DNA methyltransferases – conformational changes andallosteric regulationAlbert Jeltsch, University Stuttgart, GermanyNetworking & Refreshment Break 16:00-16:20 @ Breakout Area16:20-16:50 Title: N-acyltransferases and their role in fatty acid amide biosynthesisDavid J Merkler, University of South Florida, USA16:50-17:20 Title: Lysyl oxidase: A versatile and elusive enzymeKarlo M Lopez, California State University-Bakersfield, USA17:20-17:50 Title: ProxiMAX randomization: Precision protein engineeringAnna V Hine, Aston University, UK17:50-18:20 Title: Stability and function of a thermophilic cytochrome c’Sotaro Fujii, Hiroshima University, JapanNetworking and Award CeremonyPanel DiscussionDay 2 March 06, 2018ArmstrongKeynote Forum10:00-10:40Title: Principles of profiling as applicable to the infrastructure of continuous education systemto impact for having drug designe to suit an innovative model of translational pipelineSergey Suchkov, I M Sechenov First Moscow State Medical University, RussiaNetworking & Refreshment Break 10:40-11:00 @ Breakout Area11:00-11:40Title: Plasmonic biosensors on demand: Tunable penetration depth, compactness, ultrahighsensitivity and enhanced spectroscopiesIbrahim Abdulhalim, Ben-Gurion University of the Negev, Israel11:40-12:20 Title: Thermophilic enzymes with applications for industrial biocatalysisJennifer A Littlechild, University of Exeter, UK12:20-13:00Title: How urease accessory proteins coupled GTP hydrolysis/binding to nickel delivery tourease?Kam Bo Wong, The Chinese University of Hong Kong, ChinaLunch Break 13:00-14:00 @ RBGPoster Presentations @ Foyer 14:00-14:30PS 1 Title: Inhibition of Lysyl oxidase in breast cancer cells by small-molecule inhibitorsKathryn A Johnston, California State University, USAPS 2Title: Design, construction and extracellular expression of L-asparaginase from Dickeyachrysanthemi in yeastBrian Effer, University of La Frontera, ChilePS 3Title: Study of the potential use of antifreeze proteins of Deschampsia antarctica in thecryopreservation of Salmo salar spermatozoaShort S, Universidad de La Frontera, ChilePS 4Title: Characterization of antifreeze activity in apoplastic extract of DeschampsiaantarcticaFarías J G, Universidad de La Frontera, ChilePS 5Title: Computer aided screening of mangrove ecosystem derived compound againstacetyl-cholinesteraseShahid ullah, Shenzhen University, ChinaSessions: Molecular Enzymology | Enzyme Therapeutics |Enzymology in drug discovery | IndustrialBiotechnology|Biotechnology ApplicationsSession Chair: Jennifer A Littlechild, University of Exeter, UKSession Co-Chair: Shree Kumar Apte, Bhabha Atomic Research Centre, IndiaSession Introduction14:30-15:00 Title: Engineering cyanobacterial nitrogen bio-fertilizer for rice cultivation in stressful environmentShree Kumar Apte, Bhabha Atomic Research Centre, India15:00-15:30 Title: The dual role of integrase in HIV-1 replicationMamuka Kvaratskhelia, University of Colorado School of Medicine, USA15:30-16:00Title: Characterization of cystathionine γ-lyase from T. gondii: A target for drugdevelopment?Alessandra Astegno, University of Verona, ItalyPage 4Networking & Refreshment Break 16:00-16:20 @ Breakout Area16:20-16:50 Title: Infulence of four kinds of additives and concentration on oats silage effectYungui Yang, Northwest A & F University, China16:50-17:20Title: Enhanced production of Bacillus thuringiensis subspecies israelensis delta endotoxinby the use of rotten pineapple juice and fish-amino acid as medium ingredientsC Gopinathan, University of calicut, India17:20-17:40Title: Structure/function of 3’-phosphoadenosine 5’-phosphosulfate (PAPS) synthase(PAPSS)K V Venkatachalam, Nova Southeastern University, USA (VP)Networking and Award CeremonyDay 3 March 07, 2018 Extended Networking & Lunch 12:30-13:30 @ Restaurant
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